Henoch Schonlein Purpura Mimicking Lupus Nephritis- A Rare Case

نویسندگان

  • Amieleena Chhabra
  • Tapas Baikar
  • Vivek Dewan
  • Tribhuvan Pal Yadav
چکیده

Introduction Henoch Schonlien Purpura(HSP ),the most common non granulomatous ,immune complex mediated small vessel vasculitis in children involves multiple organs [1–2]. In adults and infants less than 2 years it tends to have an atypical course with higher rate of gastrointestinal and renal complications [1]. HSP nephritis is reported to occur in 20-80% of patients and characterized by mesangial or mesangioproliferative glomerulonephritis with varying degree of hypercelullarity Rapidly progressive glomerulonephritis is rare in children with HSP. One to seven percent patients suffer from end stage renal disease [3,4]. On Imunofluoroscence renal biopsy shows, predominantly granular deposits of IgA in the mesangium and to a lesser extent IgG or IgM deposits [5]. Full house on inmmunofluorosence is the term given to the characteristic histological findings in lupus nephritis which include glomerular deposits of IgG, IgM, IgA, C3, C4 and C1q [6]. We report a case of HSP who presented with edema over dorsum of hands and feet, arthritis and immune complex mediated rapidly progressive nephritis with full house picture on immunofluoroscencea rare occurrence. Abstract

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تاریخ انتشار 2015